Browsing by Author "Castillo, Karen"

Now showing items 1-5 of 5

    • Ca2+-dependent K+ channels from rat olfactory cilia characterized in planar lipid bilayers 
      Castillo, Karen; Bacigalupo Vicuña, Juan; Wolff Fernández, José (ELSEVIER SCIENCE BV, 2005-03-14)
      Olfactory cilia contain cyclic nucleotide-gated and Ca2+-dependent Cl- conductances that underlie excitatory chemotransduction, and a Ca2+-dependent K+ (K-Ca) conductance, apparently involved in inhibitory transduction. ...
    • Cellular & molecular Ca2+ microdomains in olfactory cilia support low signaling amplification of odor transduction 
      Castillo, Karen; Restrepo, Diego; Bacigalupo Vicuña, Juan (2010)
      Signal transduction depends critically on the spatial localization of protein constituents. A key question in odor transduction is whether chemotransduction proteins organize into discrete molecular complexes throughout ...
    • Control of lysosomal-mediated cell death by the pH-dependent calcium channel RECS1 
      Pihan, Philippe; Lisbona, Fernanda; Borgonovo, Janina Edith; Edwards Jorquera, Sandra Sofía; Nunes Hasler, Paula; Castillo, Karen; Kepp, Oliver; Urra, Hery; Saarnio, Suvi; Vihinen, Helena; Carreras Sureda, Amado; Forveille, Sabrina; Sauvat, Allan; De Giorgis, Daniela; Pupo, Amaury; Rodríguez, Diego A.; Quarato, Giovanni; Sagredo, Alfredo; Lourido Araneda, María Fernanda; Letai, Anthony; Latorre, Ramón; Kroemer, Guido; Demaurex, Nicolás; Jokitalo, Eija; Concha Nordemann, Miguel Luis Angel; Glavic Maurer, Alvaro Alberto; Green, Douglas R.; Hetz Flores, Claudio Andrés (Amer Assoc Advancement Science, 2021)
      Programmed cell death is regulated by the balance between activating and inhibitory signals. Here, we have identified RECS1 (responsive to centrifugal force and shear stress 1) [also known as TMBIM1 (transmembrane BAX ...
    • Effect of iron on the activation of the MAPK/ERK pathway in PC12 neuroblastoma cells 
      Muñoz, Pablo; Zavala, Gabriela; Castillo, Karen; Aguirre, Pabla; Hidalgo Tapia, María Cecilia; Núñez González, Marco (2006)
      Recent evidence suggests that reactive oxygen species function as second messenger molecules in normal physiological processes. For example, activation of N-Methyl-D-Aspartate receptor results in the production of ROS, ...
    • Plasma membrane Ca2+-ATPase in the cilia of olfactory receptor neurons: Possible role in Ca2+ clearance 
      Castillo, Karen; Delgado Arriagada, Ricardo; Bacigalupo Vicuña, Juan (BLACKWELL, 2007-09-03)
      Olfactory sensory neurons respond to odorants increasing Ca2+ concentrations in their chemosensory cilia. Calcium enters the cilia through cAMP-gated channels, activating Ca2+-dependent chloride or potassium channels. ...